KTR-755

Humanized Anti-HER2/neu (Herceptin/trastuzumab) ELISA Kit

Description

This test kit is intended for use in the quantitative determination of Herceptin levels in human serum or EDTA plasma.

Background


Herceptin (Trasuzumab) is a humanized monoclonal antibody used in cancer treatment for Human Epidermal Growth Factor Receptor 2 (HER2) over-expressing tumors. In the case of these tumors, Herceptin binds to and inhibits tumor growth. Herceptin can also be labeled with various toxins to enhance tumor suppression. Studies have also found that Herceptin targets gastric cancer stem cells characterized by CD90 phenotype.

 This test kit was developed for the measurement of Herceptin (Trastuzumab). However, all the ADC (Antibody Drug Conjugate) drug using Herceptin as carrier antibody can be measured with this assay. These ADC drugs include Trastuzumab emtansine (KADCYLA), Trastuzumab deruxtecan (ENHERTU), etc.
​​​​​​​
For research use only. Not for use in diagnostics procedures.

Specifications

Catalog no. KT-755
Target Humanized anti-Her2/neu (Herceptin/trastuzumab)
Species Human
Method Sandwich ELISA
Tests Per Kit 96 tests
Detection Colorimetric
Sensitivity / LLOD 0.245 ng/mL
Dynamic Range 1 - 500 ng/mL
Total Incubation Time 1 hour, 50 minutes
Sample Type serum, EDTA plasma
Sample Volume 10 µL
Storage Temperature 2-8 °C
For research use only. Not for use in diagnostics procedures.